Research Projects

Research Projects

LOCUS MEDICUS

LOCUS-MEDICUS’s contribution to the Greek and International scientific community is proven in practice with more than 20 international (and 8 Greek) publications in reputable scientific journals and with more than 30 participations in Greek and international scientific conferences (3 conference awards).

Also, the extensive research activity of LOCUS-MEDICUS laboratories includes a large number of scientific collaborations in diagnostic and research level with international organizations and Greek Universities, Institutions and Hospitals. Indicatively, some of the most important research collaborations of the last years are mentioned:

WHO (World Health Organization): Establishment of the Global Laboratory Network for the detection and standardization of HPV.

WHO: Evaluation of CMV Molecular Analyses.

WHO: Evaluation of EBV Molecular Analyses.

Medical School of the University of Athens and the Hospital “SOTIRIA”: “Study of the expression of indicators of natural immunity in patients with tuberculosis” and “Molecular study of the analysis of Mycobacterium genotypes in Greece”.

University of Thrace, Alexandroupolis Hospital, Onassis Cardiac Surgery Center and University of Athens: “Association between chlamydia and herpes viruses with the occurrence of myocarditis”.

University of Thessaly, Theageneio Cancer Hospital and University of Athens: “Comparison of HPV genotyping methods in Greece”.

Athens Ophthalmology Clinic and Athens General State Hospital: “Association of LOXL1 gene polymorphisms in Greek patients with Pseudo-exfoliative Syndrome”.

Series of research protocols with the Hospitals of Evangelismos, Voula and Children “Aglaia Kyriakou”.

Finally, the company LOCUS-MEDICUS supports the young Greek scientists by making available to them both the material and technical infrastructure of its laboratories, as well as the know-how of its executives. In practice this corresponds to:

Direct participation in 7 Doctoral dissertations of young scientists.

3 Masters of postgraduate students (One with distinction and monetary prize).

2 Placement of students from Universities of Great Britain.

Invitations of LOCUS MEDICUS scientists for development of lectures in more than 60 scientific meetings of postgraduate level.

A large number of internships for graduates of universities and technical institutes.

Quality, safety and innovation lead the company to long-term benefits, which are always more important than the short-term ones.

It should be noted that to date, all the investments of the company LOCUS MEDICUS AIE have been achieved with own funds, as well as with financial State and European support from the Regional Operational Programs 3rd CSF and NSRF 2007-2013 for the support of Small and Very Small Enterprises of the Tertiary Sector for service activities.

Publications in international scientific journals

Improvement of Sperm Quality in Hyperviscous Semen following DNase I Treatment.

Effrosyni Nosi, Angelos D. Gritzapis, Konstantinos Makarounis, Georgios Georgoulias, Vasilios Kapetanios, Marighoula Varla-Leftherioti, Panagiotis Venieratos, Christodoulos Papanikopoulos, Anastasia Konstantinidou, and Vassilis Tsilivakos.

Flow cytometry analysis of CD4+IFN-γ+ T-cells for the diagnosis of mycobacterium tuberculosis infection.

Papageorgiou CV, Anastasopoulos A, Ploussi M, Leventopoulos M, Karabela S, Fotiadis K, Papavasileiou A, Vogiatzakis E, Ioakeimidis D, Gritzapis AD, Poulakis N.

Cytometry B Clin Cytom. 2016 May;90(3):303-11. doi: 10.1002/cyto.b.21275. Epub 2015 Sep 8.

Intracellular ESAT-6: A new biomarker for Mycobacterium tuberculosis infection.

Poulakis N, Gritzapis AD, Ploussi M, Leventopoulos M, Papageorgiou CV, Anastasopoulos A, Constantoulakis P, Karabela S, Vogiatzakis E, Tsilivakos V.

Cytometry B Clin Cytom. 2016 May;90(3):312-4. doi: 10.1002/cyto.b.21220. Epub 2015 Feb 6.

Molecular investigation of menstrual tissue for the presence of C. Trachomatis, M. Hominis and U.Urealyticum collected by women with a history of infertility.

Michou I. V, Constantoulakis P., Makarounis K., Georgoulias G., Kapetanios V., Tsilivakos V. The Journal of Obstetrics and Gynaecology Research. 2013 (early on-line version doi:10.1111/jog.12165).

Department of Molecular Pathology and Genetics, Locus Medicus Laboratory, Athens, Greece.
Department of Infertility, Locus Medicus Laboratory, Athens, Greece.
Embryology and Histology Department, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Successful bone marrow transplantation in a pediatric patient with chronic myeloid leukemia from a HLA-identical sibling selected by preimplantation HLA testing.

Goussetis E., Constantoulakis P., Kitra V., Peristeri I., Baka M., Papadimitropoulos M., Karamolegos C., Paisiou A., Vasilatou-Kosmidis H., Graphakos S., Pediatr. Blood Cancer. 2011 Aug;57(2):345-7. doi: 10.1002/pbc.23007. Epub 2011 Mar 24.. 2011 (in Press).

Locus Medicus S.A., Athens, Greece.
Stem Cell Transplant Unit, Aghia Sophia Children’s Hospital, Athens, Greece.
Embryogenesis S.A., Athens, Greece.

MIRU-VNTR typing of drug-resistant tuberculosis isolates in Greece.

Nikoletta Rovina, Simona Karabela, Pantelis Constantoulakis, Vassiliki Michou, Konstantinos Konstantinou, Vassileios Sgountzos, Charis Roussos and Nikolaos Poulakis. Adv Respir Dis, 7 April 2011.

Locus Medicus Laboratory, Athens, Greece.
1st University Pulmonary Department, Medical School, National and Kapodistrian University of Athens ‘SOTIRIA’ District Chest Diseases Hospital, 152 Mesogion Street, 11527 Athens, Greece.

Ιn vivo expression of innate immunity markers in patients with mycobacterium tuberculosis infection.

Pantelis Constantoulakis, Eftihia Filiou, Nikoletta Rovina, George Chras, Aggeliki Hamhougia, Simona Karabela, Adamandia Sotiriou, Charis Roussos, Nikolaos Poulakis. BMC Inf. Dis. 2010, 10:243.

Locus Medicus, Molecular Pathology and Genetics Dept., Athens, Greece.

Αcute apenditis in patient with acute promyelocytic leukemia.

Papageorgiou SG, Foukas P, Economopoulou C, Tsirigotis P, Sakorafas G, Georgakopoulos N, Kefala M, Pappa V, Economopoulos T, Panayiotides I, Papageorgiou E, Dervenoulas (2011) J. Leuk Res. Jan;35(1):e4-5. Epub 2010 Sep 19

Locus Medicus Laboratory, Athens, Greece.
Second Department of Internal Medicine, Propaedeutic, Haematology Unit, University General Hospital “Attikon”, Haidari, Greece.

Are Educators at High Risk of Sub-fertility? A Multicenter Study.

Perros G., Tzonis P., Tsilivakos V., Gerofotis A., Dalavitsou V., Vassilaki A., Keramitsoglou T., Papaioannou D., Moschandreou D., Kontopoulou-Antonopoulou V., Daniilidis M., Varla-Leftherioti M. (2011) Am J Reprod Immunol.Apr;65(4):415-20. Epub 2010 Aug 16.

Locus Medicus Laboratory, Athens, Greece.
Immunobiology Dept “Helena Venizelou” Maternity Hospital, Athens, Greece.

Herpes Virus Infected Spermatozoa Following Density Gradient Centrifugation for IVF Purposes.

Michou V., Liarmakopoulou S., Thomas D., Tsimaratou K., Makarounis K., Constantoulakis P., Angelopoulou R., Tsilivakos V. (2011). Andrologia (early on-line version).

Locus Medicus Laboratory, Athens, Greece.
Diagnosi-IVF, Athens, Greece.
National and Kapodistrian University of Athens, Pathophysiology Clinic, Endocrine Unit, Athens, Greece.
National and Kapodistrian University of Athens, Embryology and Histology Department, Athens, Greece.

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In Vivo Expression of Innate Immunity Markers in Patients with Mycobacterium Tuberculosis Infection.

Constantoulakis P., Filiou E., Rovina N., Chras G., Hamhougia A., Karabela S., Sotiriou A., Roussos C., Poulakis N. (2010). BMC Infect Dis., 10, 243.

Locus Medicus, Molecular Pathology and Genetics Dept., Athens, Greece.

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Myocardial Inflammation in Duchenne Muscular Dystrophy as a Precipitating Factor for Heart Failure: a Prospective Study.

Mavrogeni S., Papavasiliou A., Spargias K., Constandoulakis P., Papadopoulos G., Karanasios E., Georgakopoulos D., Kolovou G., Demerouti E., Polymeros S., Kaklamanis L., Magoutas A., Papadopoulou E., Markussis V., Cokkinos DV. (2010). BMC Neurol.,10, 33.

Locus Medicus Laboratory, Athens, Greece.
Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece.

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Wound Healing After Laser Skin Resurfacing: The Effect of a Silver Sulfadiazine-Hyaluronic Acid-Containing Cream Under an Occlusive Dressing.

Kontoes P.P., Vrettou C.P., Loupatatzi A.N., Marayiannis K.V., Foukas P.G., Vlachos S.P. (2010). J Cosmet Laser Ther. 12(1), 10-3.

Locus Medicus Laboratory, Athens, Greece.
Laserlight Clinic, Athens, Greece.

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Sequence-Based Genotyping HPV L1 DNA and RNA Transcripts in Clinical Specimens.

Satra M., Vamvakopoulou D.N., Sioutopoulou D.O., Kollia P., Kiritsaka A., Sotiriou S., Antonakopoulos G., Alexandris E., Costantoulakis P., Vamvakopoulos N.C. (2009) Pathol Res Pract., 205(12):863-9.

Locus Medicus Laboratory, Athens, Greece.
Department of Biology and Genetics, University of Thessalia Medical School, Larisa, Greece.

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Myocardial Inflammation in Autoimmune Diseases: Investigation by Cardiovascular Magnetic Resonance and Endomyocardial Biopsy.

Mavrogeni S., Spargias K., Markussis V., Kolovou G., Demerouti E., Papadopoulou E., Stavridis G., Kaklamanis L., Douskou M., Constantoulakis P., Cokkinos DV. (2009). Inflamm Allergy Drug Targets., 5, 390-7.

Locus Medicus Laboratory, Athens, Greece.
Onassis Cardiac Surgery Center, Athens, Greece.

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Endomyocardial HSV-II Detection in an Infant with Dilated Cardiomyopathy.

Mantadakis E., Thomaidis S., Thomaidis A., Constantoulakis P., Rammos S., Chatzimichael A. (2009) J. Clin. Virol. (in Press).

Locus Medicus Laboratory, Athens, Greece.

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Detection of Herpes Virus DNA in Post-Operative Thyroid Tissue Specimens of Patients with Autoimmune Thyroid Disease.

Thomas D, Liakos V, Michou V, Kapranos N, Kaltsas G, Tsilivakos V, Tsatsoulis A. (2008). Exp Clin Endocrinol Diabetes. 116(1), 35-9.

Locus Medicus Laboratory, Athens, Greece.
Department of Endocrinology, Diabetes and Metabolism, Metaxa Memorial Anticancer Research Hospital, Piraeus, Greece.

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Fatal Disseminated Bocavirus Infection in a Young Transplant Patient.

Kyriazi V., Manaka A., Balotis C-G., Konstandoulakis P., Baltadakis I., Karakasis D., Apostolidis I., Harhalakis N., Nikiforakis E. (2008) Int J Infectious Disease., 12, S18-S18.

Locus Medicus Laboratory, Athens, Greece.
BMT Unit, Evaggelismos Hospital, Athens, Greece.

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Evidence for Association of the G1733A Polymorphism of the Androgen Gene with Recurrent Spontaneous Abortions.

Karvela M., Stefanakis N., Papadopoulou S., Tsitilou S.G., Tsilivakos V., Lamnissou K. (2008). Fertil Steril., 90(5):2010.e9-2010.e12.

Locus Medicus Laboratory, Athens, Greece.
Department of Biology, Division of Genetics and Biotechnology, University of Athens, Athens, Greece.

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Expression of Oncofetal RNA-Binding Protein CRD-BP/IMP1 Predicts Clinical Outcome in Colon Cancer.

Dimitriadis E., Trangas T., Milatos S., Foukas P.G., Gioulbasanis I., Courtis N., Nielsen F.C., Pandis N., Dafni U., Bardi G., Ioannidis P. (2007). Int J Cancer., 1;121(3), 486-94.

Locus Medicus Laboratory, Athens, Greece.
Department of Genetics, Saint Savvas Oncological Hospital, Athens, Greece.

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Altered Immunophenotypic Parameters in Infertile Women. Possible Role of Herpes Viremia.

Thomas D., Michou V., Moustakarias T., Aleporou V., Matzavinos T., Mitsakos-Barbagiannis K., Kalofoutis A., Tsilivakos V. (2005). Am J Reprod Immunol. 54(2), 101-11.

Locus Medicus Laboratory, Department of subfertility, Athens, Greece.

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The Effect of Valacyclovir Treatment on Natural Killer Cells of Infertile Women.

Thomas D., Michou V., Tegos V., Patargias T., Moustakarias T., Kanakas N., Mantzavinos T., Apostolidis C., Salamalekis E., Kalofoutis A., Tsilivakos V. (2004). Am J Reprod Immunol., 51(3), 248-255.

Department of subfertility, Locus Medicus Laboratory, Athens, Greece.

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Alterations in the Proliferating Compartment of Gastric Mucosa During Helicobacter Pylori Infection: The Putative Role of Epithelial Cells Expressing p27(kip1).

Sougioultzis S., Foukas P.G., Tzivras M., Kourtessas D., Gorgoulis V.G., Davaris P., Archimandritis A.J. (2003). Mod Pathol., 16(11), 1076–1085.
Locus Medicus Laboratory, Athens, Greece.

Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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Detection of Human Telomerase Reverse Transcriptase mRNA in Urine of Patients with Bladder Cancer: Evaluation of an Emerging Tumor Marker.

Melissourgos N., Kastrinakis N.G., Davilas I., Foukas P., Farmakis A., Lykourinas M. (2003). Urology., 62(2), 362-367.
Locus Medicus Laboratory, Athens, Greece.

Department of Urology, G. Gennimatas General Hospital, Athens, Greece.

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The Fraction of Peripheral Blood CD56 + /CD16 – /CD3 – Subpopulation on Total Natural Killer Cells as an Indication of Fertility-Infertility.

Michou V.I., Kanavaros P., Athanassiou V., Chronis G.B., Stabamas S., Tsilivakos V. (2003). Fertil Steril., 80 Suppl 2:691-7
Locus Medicus Laboratory, Athens, Greece.

Genetics and Biotechnology Department, Faculty of Biology, University of Athens, Ilissia, Greece.

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Expression of HLA-DR is Reduced in Tumor Infiltrating Immune Cells (TIICs) and Regional Lymph Nodes of Non-Small-Cell Lung Carcinomas. A Putative Mechanism of Tumor-Induced Immunosuppression?

Foukas P.G., Tsilivakos V., Zacharatos P., Mariatos G., Moschos S., Syrianou A., Asimacopoulos P.J., Bramis J., Fotiadis C., Kittas C., Gorgoulis V.G. (2001). Anticancer Res. 21(4A), 2609-15.

Locus Medicus Laboratory, Athens, Greece.
Department of Histology and Embryology, Medical School, University of Athens, Greece.

Publications in Greek scientific journals.

Uncommon cause of solitary palpable swelling in the axillary cavity.

E. Andriopoulou, P. Foukas, P. Konstantoulakis, G. Georgoulias, V. Tsilivakos (2008) Hellenic Surgery, 80 (6): 210.

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Lipoma of the small intestine, a cause of severe anemia

E. Andriopoulou, E. Xagiyianni, P. Foukas, P. Konstantoulakis, B. Tsilivakos (2008) Hellenic Surgery, 80 (6):210.

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Breast Cancer – Heredity-Treatment

E. Andriopoulou, V. Tsilivakos, P. Konstantoulakis, P. Foukas (2008) Hellenic Surgery, 80 (6): 44.

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Recent data in the investigation of the etiology of spontaneous miscarriages in the first trimester.

V.Tsilivakos, V.Michou, D.Thomas. (2004) Archives of Pathological Anatomy, 18 (2): 45-47.

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Histopathological and karyotypic approach of abortions. Correlation of infectious causes with immune parameters.

V. Tsilivakos, V. Michou, D. Thomas. (2004). Written Clinical Tutorial: “Six miscarriages-Laboratory investigation” 3rd Panhellenic Conference of Medical Biopathology, Thessaloniki, 31 Mar., pp. 12-15.

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Laboratory investigation of clinically observed immunosuppression of melanopaths.

Tsilivakos V. (2000). Archives of Pathological Anatomy 14 (3): 90-96 (Review).

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Organization and functionality of reactive lymphoplasmacytic infiltrates of non-small cell lung carcinomas.

A. Syrianou, L. Haldi, P. Foukas, E. Macheira, I. Papastamatiou – Tsimara, V. Tsilivakos and P. Kordopatis. (1999). Medicine 75 (4).

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Applications of flow cytometry in clinical practice. The study model of Kathexin Miscarriages of Immunological Etiology.

Tsilivakos V. (1999), Archives of Pathological Anatomy, 1 (7): 43-50 (Review).

Announcements at International Conferences

Improvement of sperm quality in hyperviscous semen following DNase I treatment.

M. Varla-Leftherioti, P. Venieratos, V. Tsilivakos, A.Gritzapis,E. Nosi,A.Konstantinidou,C. Papanikopoulos

the 35th Annual Meeting of the ESHRE, June 2019, Vienna,Austria

 

Intracellular detection of infectious pathogens in sperm cells.

Gritzapis AD, Makarounis K., Leventopoulos M, Nossi E., Nikolopoulos D., Georgoulias G., Kapetanios V., Tsilivakos V.

4th World Congress on Virology October 06-08, 2014 San Antonio, USA

 

Method of Intracellular detection of infectious pathogens in sperm cells.

Gritzapis AD, Makarounis K., Leventopoulos M, Boukakis G., Nossi E., Nikolopoulos D., Georgoulias G., Kapetanios V., Tsilivakos V.

8th European congress of Andrology, ECA Barcelona 2014.

 

Intracellular ESAT-6: a new biomarker of Mycobacterium tuberculosis infection?

Nikolaos Poulakis, Angelos Gritzapis, Vassilis Tsilivakos,Maria Ploussi, , Michail Leventopoulos, Chrysovalantis Papageorgiou, Andreas Anastasopoulos, Simona Karabela, Evangelos Vogiatzakis, Pantelis Constantoulakis.

European Respiratory Society Annual Congress, Barcelona 2013

 

Molecular fingerprinting of mycobacterium tuberculosis isolates in new cases of tuberculosis using Mycobacterial Interspersed Repetitive Unit–Variable Number Tandem Repeat Genotyping (MIRU-VNTR) – Epidemiology of drug resistant tuberculosis in Greece.

N. Rovina, S. Karabella, P. Constantoulakis, V. Michou, K. Konstantinou, V. Sgountzos, Ch. Roussos, N. Poulakis
1: Unit of Respiratory Infectious Diseases, 1st University Respiratory Clinic, Sotiria Hospital, Athens, Greece
2: National Center of Tuberculosis, Microbiology Dpt, Sotiria Hospital, Athens, Greece
3: “Locus Medicus” Research Center, Athens, Greece
4: Clinic of Multi-drug Resistant Tuberculosis, Sotiria Hospital, Athens, Greece
International conference of American thoracic society, 14-19 May, 2010 New Orleans, USA.

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In vivo expression of innate immunity markers in patients with mycobacterium tuberculosis infection.

Pantelis Constantoulakis, Eftihia Filiou, George Chras, Aggeliki Hamhougia, Simona Karabela, Nikolleta Rovina, Adamandia Sotiriou, Charalambos Roussos, Nikos Poulakis
5th Congress of the International Union Against Tuberculosis and Lung Disease, 27 – 30 May 2009, Dubrovnik – Croatia.

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Cardiovascular magnetic resonance assessment of myocarditis and comparison to histology and real time polymerase chain reaction: the emerging role of chlamydia

Sophie Mavrogeni, Menelaos Manousakis, Konstantinos Spargias, Pantelis Konstantoulakis, Genovefa Kolovou, Eftihia Demerouti, Evangelia Papadopoulou, Marouso Douskou, Haralambos Moutsopoulos and Dennis V Cokkinos
11th Annual SCMR Scientific Sessions, Los Angeles, CA, USA. 1–3 February 2008.

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Fatal disseminated bocavirus infection in a young transplant patient

1Vicky Kyriazi, 1Aikaterini Manaka, 1Constantine-George Balotis, 2Pantelis Konstandoulakis, 1Ioannis Baltadakis, 1Dimitri Karakasis, 1Ioannis Apostolidis, 1Nicholas Harhalakis, 1Emannuel Nikiforakis.
1: BMT Unit, Evaggelismos Hospital
2: Locus Medicus Laboratory, Athens, Greece
15th International Symposium on Infections in the Immunocompromised Host, June 22-25 2008, Thessaloniki, Greece.

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Fatal Disseminated Bocavirus Infection in a Young Transplant Patient

Vicky Kyriazi, Aikaterini Manaka, Constantine-George Balotis, Pantelis Konstandoulakis, loannis Baltadakis, Dimitri Karakasis, loannis Apostolidis, Nicholas Harhalakis, Emannuel Nikiforakis
International Journal of Infectious Diseases, Volume 12, Supplement 2, June 2008, Page S18

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Herpes virus presence following density gradient semen washing technique.

Liarmakopoulou S, Michou V, Thomas D, Pappa H, Argyriou T, Apostolidis C, Xidias G, Tsilivakos V.
13th World Congress on In Vitro Fertilization Assisted Reproduction and Genetics: Istanbul, Turkey, May 26-29, 2005.

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HSV infected spermatozoa following ART washing procedure.

Michou V, Liarmakopoulou S, Thomas D, Pappa H, Argyriou T, Apostolidis C, Xidias G, Tsilivakos V.
European Society Of Human Reproduction and Embryology, 21st Annual Meeting, Copenhagen, 19-22 June, 2005.

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Rapid and accurate detection of Beta-Globin Gene (HBB) mutations by Denaturing High Performance Liquid Chromatography (DHPLC).

Bournazos S, Tserka A
12th International Clinical genetics Seminar on PRENATAL DIAGNOSIS, Athens, 2004.

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Acyclovir treatment of herpes virus infected spermatozoa and possible effect on IVF outcome.

D. Thomas, V. Michou, N. Kapranos, T. Moustakarias, A. Kalofoutis, V. Tsilivakos.
18th Congress of European Society for Urological Research, 4-6 November, Athens, 2004.

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The effect of valacyclovir treatment on NK cells of women with a history of infertility.

Thomas D, Michou V, Sakarellos A, Apostolidis A, Pistofidis G, Tegos V, Moustakarias T, Kanakas N, Matzavinos T, Tsilivakos V.
4th Congress of the European society for Reproductive and Developmental Immunology. Rhodes, June 2003

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The fraction of peripheral blood CD56+/CD16+/CD3- on total natural killer cells as an indication of fertility-infertility.

Michou V, Tsilivakos V, Athanassiou V, Chronis G, Patargias T.
The 4th congress of The European Society for Reproductive and Developmental Immunology, Rhodes, 2003.

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Differences of clinical findings in aborters experiencing effortless and difficult conception.

Michou V, Chronis G, Zafiridis G, Athanassiou V, Kopsidas E, Mitsakos E, Tegos V, Tsilivakos V.
The 4th congress of The European Society for Reproductive and Developmental Immunology, Rhodes, 2003.

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Announcements at Greek Conferences

Use of DNAase I as a treatment to improve the oxidative stress of sperm in sperm characterized by high viscosity.

Nosi Efrosini, Gritzapis Angelos, Makarounis Konstantinos, Georgoulias Georgios, Captain Vassilis, Veniratos Panagiotis, Tsilimantou Anastasia, Papanikopoulos Christodoulos, Zeginiadou Theodosia, Konstantinidou Anastasia, Tsilivakos Vassilis

11th Panhellenic Andrology, May 2019, Athens.

Use of DNAase I as a treatment to improve the quality of sperm in sperm characterized by high viscosity.

E. Nosi, A.D. Gritzapis, K. Makarounis, G. Georgoulias, V. Kapetanios, K. Sfakianoudis, C. Papanikopoulos, A. Konstantinidou, V. Tsilivakos.

22nd Panhellenic Urological Conference, 2014 Heraklion, Crete. Conference Award.

In vivo expression levels of natural immunity markers in patients with tuberculosis.

P. Konstantoulakis, E. Filiou, G. Chras, A. Hamhougia, S. Karabela, N. Robina, A. Sotiriou, C. Roussos, N. Poulakis
35th Panhellenic Medical Conference, 5-9 May, 2009 Athens

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Breast cancer – heredity – treatment.

E. Andriopoulou, V. Tsilivakos, P. Konstantoulakis, P. Foukas, L. Grigorakos
6th Multidisciplinary Medical Conference of Laconia (2008), Volume of Abstracts, p. 18.

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Colon cancer: New data.

E. Andriopoulou, V. Tsilivakos, P. Konstantoulakis, P. Foukas, L. Grigorakos
6th Multidisciplinary Medical Conference of Laconia [2008], Volume of Abstracts, p. 18.

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Infection with the various HPV types in Greek women: Correlation with the degree of cytological abnormality.

P. Konstantoulakis, E. Bilirakis, G. Koliopoulos, E. Paraskevaidis
9TH Congress of International College of Outpatient Gynecology & 5th Panhellenic Congress for Colposcopy & Cervical Pathology, Athens, 2000.

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Pre-implantation selection of HLA-compatible embryo as a donor for transplantation in a child with chronic myelogenous leukemia.

Konstantoulakis P., Papadimitropoulos M., Divane A., Mastrominas M., Davies S., Baka M, Bouchoutsou D., Kosmidi E.
18th Panhellenic Hematology Conference, Thessaloniki 2007

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EHEQAS: European HPV DNA test External Quality Assurance Scheme

Neophytou PI1, 2, Ioannou N2, Brink AATP3, Snijders PJF3, Pol RP3, Constantoulakis P4, Yapijakis C5, Adamopoulou M5, Tachezy R6, Smahelova J6, Grce M7, Sabol I7, Medeiros RM8 and Konya J9

Mendel Center for Biomedical Sciences, 5 Kimonos, 2406 Egkomi, Cyprus,
P.N. Molecular Diagnosis, 5 Kimonos, 2406 Egkomi, Cyprus,
Dept. of Pathology, Vrije University Medical Center, Amsterdam, The Netherlands
Locus Medicus, 4 Sofias Sliman, 11526 Athens, Greece
Bioerevna Center, Dept. of Molecular Biology , 4 Marni, 10433 Athens, Greece
Inst. Hematol. & Blood Transfusion, National Ref. Lab for Papillomaviruses, Prague, Czech Republic
Lab. Mol. Virol. & Bacteriol., R. Boskovic Institute, Div. Mol. Medicine, Zagreb, Croatia
Portuguese Inst. of Oncology, Mol. Oncology & Virology Lab, Porto, Portugal
Dept. of Medical Microbiology, Medical School, Univ. of Debrecen, Hungary
EUROGIN CONGRESS, MONACO, OCT 4-6, 2007

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Identification of cytological diagnosis by PCR-DNA Chlamydia trachomatis in orthopharyngeal material with negative culture findings.

Davou-Zourdou Konstantina, Papageorgiou Stratos, Katsou Georgia, Hesketh Graham, Konstantoulakis Pantelis, Androulakis Michalis.
Γ.Ν. Voula Asclepieion, Department of Cytology, Department of Otolaryngology, Department of CT
Scan Locus Medicus Polyclinic.
Panhellenic Conference on Otolaryngology – Head and Cervical Surgery. Thessaloniki, 15-19 November 2007

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Epidemiology of HPV infection of the cervix in Greece. Presentation of 4,306 cases in the last decade.

Konstantoulakis P., Aranitis V., Michou B, Kastrinakis N., Mortakis A., Monemvasitis G., Mitsakos K., Papadopoulou K., Thodou E., Tegos V., Kolonas V., Bilirakis E., Foukas P.
7th Scientific Meeting for the Prevention of Gynecological Cancer, Thessaloniki 2006

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HPV-DNA detection in 4,306 cervical smears and biopsy materials. Comparison of collection methods.

Bilirakis E., Foukas P., Aranitis V., Thodou E., Konstantoulakis P.
7th Scientific Meeting for the Prevention of Gynecological Cancer, Thessaloniki 2006

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Study of HPV infection in male population.

Melissourgos N., Aranitis V., Michou V., Foukas P., Konstantoulakis P.
7th Scientific Meeting for the Prevention of Gynecological Cancer, Thessaloniki 2006

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HPV-DNA detection in 4,715 cervical smears and biopsy materials. Comparison of collection methods and presentation of the new technique of DNA microarrays.

Konstantoulakis P., Aranitis V., Michou B, Thodou E., Astara E., Kardamaki A., Bilirakis E., Mortakis A., Monemvasitis G., Mitsakos K., Papadopoulou K. Tegos V., Kolonas V., Foukas P.
7th Panhellenic Congress of Cytology, Volos 2006.

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A Case of transmission of herpes virus from father to fetus.

Thomas Dimitrios, Michou Vasiliki, Tzeferakos Alexandros, Sakellariou Maria, Kalofoutis Anastasios, Tsilivakos Vassilis.
9th Panhellenic Pathological Conference, Kavala June 24-26, 2004.

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Peripheral blood lymphocyte subpopulations in women with a history of infertility. The role of subclinical herpes zoster viremia in immunological parameters.

D. Thomas, V. Michou, T. Moustakarias, T. Patargias, A. Kalofoutis, V. Tsilivakos.
6th Panhellenic Congress of Immunology, Thessaloniki 8-11 December 2004.

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A new approach to endometritis due to infertility-related infectious agents.

Michou B, Zafeiridis C, Kopsidas E, Sakarellos A, Tegos B, Athanassiou B, Mousia M, Tsilivakos V.
8th Panhellenic Conference of Pathological Anatomy. 2002, Volos.

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The role of Tumor-infiltrating lymphocytes (TILs) and the need for a new histological classification of them in cutaneous melanoma.

K.Fragkia, E. Messini, P. Foukas, V. Tsilivakos, L. Haldi, MC Jr Mihm.
8th Panhellenic Conference of Pathological Anatomy. 2002, Volos

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Description and clinical significance of the presence of K-lymphocytes in the endometrium and the corresponding cells in the blood of fertile and infertile women.

Michou B, Margomenou A, Tsitsiloni O, Stampamas S, Athanassiou B, Chronis C, Stylianidou A, Stefanaki S, Tsilivakos V.
8th Panhellenic Conference of Pathological Anatomy. 2002, Volos

(FIRST CONFERENCE PRIZE WITH MONETARY PRIZE)

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Anti-herpes therapy in NK lymphocytes of women with a history of infertility.

Thomas D, Michou B, Sakarellos A, Apostolidis A, Pistofidis C, Tegos B, Moustakarias I, Kanakas N, Mantzavinos I, Tsilivakos V.
2nd Panhellenic Conference of the Hellenic Society of Fertility and Infertility, Thessaloniki, 6-8 December.

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Immunophenotypic determination and clinical significance of the presence of K-lymphocytes in the secretory endometrium and in the blood in fertile women and in women with a history of infertility.

Tsilivakos B, Michou B, Margomenou A, Tsitsiloni O, Stampamas S., Andriopoulou K, Athanassiou B, Chronis C, Stylianidou A, Stefanaki S.
First Prize at the 8th Panhellenic Conference of Pathological Anatomy. University of Thessaly, 2002.

(FIRST CONFERENCE PRIZE)

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Differences in laboratory findings in the investigation of miscarriages in the ground of easy and of difficult conception

Michou B, Chronis C, Athanassiou B, Kopsidas E, Mitsakos K, Tegos B, Tsilivakos B.
20 Panhellenic Conference of the Hellenic Society of Fertility and Infertility, Thessaloniki, 2002.

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The fraction of CD56 + CD16-CD3- cells to total NK (Natural Killers) of the peripheral blood, as a criterion of fertility-infertility.

Vasiliki Michou, Vassilis Tsilivakos, Vassilis Athanassiou, George V. Chronis, Stelios Stampamas, Panagiotis Kanavaros.
Second Panhellenic Conference on Molecular Pathology in Health, Athens 2001.

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Distinctive mono-hormone-producing tumors. a) adrenal cortex (Testosteronoma?) b) testis from Sertoli cells (Estrogenoma?).

S. Panageas, E. Karga, K. Pantsiotou, V. Tsilivakos, A. Michalopoulou, D. Isaiadis, I. Efstratiou, E. Papagianni, A. Bouras and P. Theodorakopoulos.
7th Panhellenic Conference of Pathological Anatomy. April 2000, Athens

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